Monogenic Obesity in Children: Current Perspectives and Clinical Implications

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Cristianne Confessor Castilho Lopes
Vitor Ohana Marques Azzini
Natascha Szumsztajn Beker
Eduardo Barbosa Lopes
Lucas Castilho Lopes
Maria Eduarda Castilho Lopes
Fábio Herget Pitanga
Larissa Silva Guimarães

Abstract

Introduction: Monogenic obesity is characterized by a mutation in a single gene, which directly influences metabolism, appetite control or other biological pathways associated with body weight regulation.


Objective: To provide practical insights for healthcare professionals working with affected children to improve health outcomes and quality of life.


Methods: This study constitutes a systematic review, classified as exploratory and descriptive. The preparation of the research was a bibliographical search in electronic databases on methods associated with RSL (Systematic Literature Review) and the applications of SMARTER (Simple Multi-Attribute Rating Technique using Exploiting Rankings).


Results: A comprehensive systematic search of the literature yielded a total of 4125 articles referring to the incidence of obesity and overweight in adolescents, of which 20 articles were eligible to be included in this systematic review.


Conclusion: With a continued and coordinated effort, it is possible to significantly improve health outcomes for these children, preparing them for a brighter future.

Article Details

How to Cite
Cristianne Confessor Castilho Lopes, Vitor Ohana Marques Azzini, Natascha Szumsztajn Beker, Eduardo Barbosa Lopes, Lucas Castilho Lopes, Maria Eduarda Castilho Lopes, Fábio Herget Pitanga, & Larissa Silva Guimarães. (2024). Monogenic Obesity in Children: Current Perspectives and Clinical Implications. International Journal of Medical Science and Clinical Research Studies, 4(06), 1054–1058. https://doi.org/10.47191/ijmscrs/v4-i06-10
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