Comprehensive Review of Shone's Syndrome: Pathophysiology, Clinical Manifestations, and Management Strategies
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Abstract
Shone's syndrome, a rare congenital heart disease, encompasses a complex array of obstructive lesions within the left heart. First described in 1963, this syndrome typically presents with a combination of supravalvular mitral ring, parachute mitral valve, subaortic stenosis, and coarctation of the aorta. The intricate nature of these anomalies presents significant diagnostic and therapeutic challenges. This review aims to elucidate the pathophysiological mechanisms underlying Shone's syndrome, provide a detailed account of its clinical manifestations, and discuss current management strategies, including surgical and medical interventions. Through an in-depth analysis of existing literature, we seek to enhance understanding and improve outcomes for patients afflicted with this multifaceted condition.
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