Micropapillary Variant of Invasive Mucinous Carcinoma - A Case Report and Review of Literature

Article Sidebar

PDF
Published: Apr 18, 2022
DOI: https://doi.org/10.47191/ijmscrs/v2-i4-04
Keywords:
.

Main Article Content

Dr. Unnimaya K S
Junior resident, Department of Pathology, Government medical college, Thiruvananthapuram, Kerala, India.
Dr. Jaimie Anandan
Assistant professor, Department of Pathology, Government medical college, Thiruvananthapuram, Kerala, India.
Dr. Lilarani Vijayaraghavan
Professor and Head of the Department, Department of Pathology, Government medical college, Thiruvananthapuram, Kerala, India.

Abstract

Invasive micropapillary variant of mucinous carcinoma breast is an under-recognized category which shares features of both pure mucinous carcinoma and invasive micropapillary carcinoma. Due to its greater propensity for nodal metastasis and angioinvasion, the prognosis in this subtype is worser than pure mucinous carcinoma breast. Here we report a case of invasive micropapillary variant of mucinous carcinoma breast in a 43-year-old female.

Article Details

How to Cite
Dr. Unnimaya K S, Dr. Jaimie Anandan, & Dr. Lilarani Vijayaraghavan. (2022). Micropapillary Variant of Invasive Mucinous Carcinoma - A Case Report and Review of Literature. International Journal of Medical Science and Clinical Research Studies, 2(4), 274–279. https://doi.org/10.47191/ijmscrs/v2-i4-04
Issue
Vol. 2 No. 4 (2022): Volume 02 Issue 04 April 2022
Section
Articles
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

References

I. Collins K, Ricci A. Micropapillary variant of mucinous breast carcinoma: A distinct subtype. Breast Journal. 2018;24(3). doi:10.1111/tbj.12935

II. Tan PH, Ellis I, Allison K, et al. The 2019 World Health Organization classification of tumours of the breast. Histopathology. 2020;77(2):181-185. doi:10.1111/his.14091

III. Asano Y, Kashiwagi S, Nagamori M, et al. Pure Mucinous Breast Carcinoma with Micropapillary Pattern (MUMPC): A Case Report. Case Reports in Oncology. 2019;12(2). doi:10.1159/000501766

IV. Yuan JP, Yan HL, Gao LK, Liu L, Rao J. Mucinous variant of invasive micropapillary carcinoma of breast: Report of two cases and literature review. International Journal of Clinical and Experimental Pathology. 2017;10(10).

V. Barbashina V, Corben AD, Akram M, Vallejo C, Tan LK. Mucinous micropapillary carcinoma of the breast: An aggressive counterpart to conventional pure mucinous tumors. Human Pathology. 2013;44(8). doi:10.1016/j.humpath.2013.01.003

VI. Kim HJ, Park K, Kim JY, Kang G, Gwak G, Park I. Prognostic significance of a micropapillary pattern in pure mucinous carcinoma of the breast: Comparative analysis with micropapillary carcinoma. Journal of Pathology and Translational Medicine. 2017;51(4). doi:10.4132/jptm.2017.03.18

VII. Ng WK. Fine-needle aspiration cytology findings of an uncommon micropapillary variant of pure mucinous carcinoma of the breast: Review of patients over an 8-year period. Cancer. 2002;96(5). doi:10.1002/cncr.10747

VIII. Madur B, Shet T, Chinoy R. Cytologic findings in infiltrating micropapillary carcinoma and mucinous carcinomas with micropapillary pattern. Acta Cytologica. 2007;51(1). doi:10.1159/000325678

IX. Liu F, Yang M, Li Z, et al. Invasive micropapillary mucinous carcinoma of the breast is associated with poor prognosis. Breast Cancer Research and Treatment. 2015;151(2):443-451. doi:10.1007/s10549-015-3413-4

X. Shet T, Chinoy R. Presence of a micropapillary pattern in mucinous carcinomas of the breast and its impact on the clinical behavior. Breast Journal. 2008;14(5). doi:10.1111/j.1524-4741.2008.00616.x

XI. Madur B, Shet T, Chinoy R. Cytologic findings in infiltrating micropapillary carcinoma and mucinous carcinomas with micropapillary pattern. Acta Cytologica. 2007;51(1). doi:10.1159/000325678

XII. Bhattacharjee K, Valiathan M. Mucinous Carcinoma of the breast with micropapillary pattern and psammomatous calcification: A case study. Journal of Pathology of Nepal. 2021;11(1). doi:10.3126/jpn.v11i1.30950

XIII. CAPELLA C, EUSEBI V, MANN B, AZZOPARDI JG. Endocrine differentiation in mucoid carcinoma of the breast. Histopathology. 1980;4(6). doi:10.1111/j.1365-2559.1980.tb02957.x

XIV. Komaki K, Sakamoto G, Sugano H, Morimoto T, Monden Y. Mucinous carcinoma of the breast in Japan. A prognostic analysis based on morphologic features. Cancer. 1988;61(5). doi:10.1002/1097-0142(19880301)61:5<989::AID-CNCR2820610522>3.0.CO;2-E

XV. Lacroix-Triki M, Suarez PH, Mackay A, et al. Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type. Journal of Pathology. 2010;222(3). doi:10.1002/path.2763

XVI. Pareja F, Lee JY, Brown DN, et al. The Genomic Landscape of Mucinous Breast Cancer. Journal of the National Cancer Institute. 2019;111(7). doi:10.1093/jnci/djy216

XVII. Natrajan R, Wilkerson PM, Marchiò C, et al. Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast. Journal of Pathology. 2014;232(5). doi:10.1002/path.4325

XVIII. Pareja F, Selenica P, Brown DN, et al. Micropapillary variant of mucinous carcinoma of the breast shows genetic alterations intermediate between those of mucinous carcinoma and micropapillary carcinoma. Histopathology. 2019;75(1). doi:10.1111/his.13853

XIX. Wong CC, Martincorena I, Rust AG, et al. Inactivating CUX1 mutations promote tumorigenesis. Nature Genetics. 2014;46(1). doi:10.1038/ng.2846