Revisiting the Pathophysiology of Acute Respiratory Distress Syndrome in Burn with Inhalation Injury: A Comprehensive Review

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Published: Feb 26, 2024
DOI: https://doi.org/10.47191/ijmscrs/v4-i02-34
Keywords:
acute respiratory distress syndrome (ARDS) burn injury inhalation injury pathophysiology inflammatory response immune cells cytokines diagnostic modalities ventilation therapy pharmacological therapy

Main Article Content

Sigit Kren Fino
Shanxi Medical University, People’s Republic of China
Nathasya Fernanda
Intern in Department of Plastic Surgery, Margono Soekarjo County Hospital, Indonesia
Michele Gondokesumo
Intern in Department of Plastic Surgery, Margono Soekarjo County Hospital, Indonesia
Ahmad Fawzy
Department of Plastic Surgery, Faculty of Medicine, University of Jenderal Soedirman – Margono Soekarjo Hospital, Indonesia

Abstract

Acute respiratory distress syndrome (ARDS) is a common complication in severe burn patients, arising from inflammatory responses following burns or inhalation injuries. This literature review explores the mechanisms and diagnostic approaches for ARDS in burn patients. Methods involved searching open-access journals using specific keywords on PubMed, Google Scholar, and Elsevier. The review highlights the involvement of various immune cells and cytokines in ARDS pathophysiology, with diagnostic tools including clinical signs, imaging, and bronchoscopy. Therapeutic strategies focus on ventilation and pharmacological interventions targeting inflammation. Further research is needed to better understand ARDS in burn patients, particularly regarding inflammatory markers and pharmacological treatments.


 

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How to Cite
Fino, S. K., Fernanda, N. ., Gondokesumo, M. ., & Fawzy, A. . (2024). Revisiting the Pathophysiology of Acute Respiratory Distress Syndrome in Burn with Inhalation Injury: A Comprehensive Review. International Journal of Medical Science and Clinical Research Studies, 4(02), 345–358. https://doi.org/10.47191/ijmscrs/v4-i02-34
Issue
Vol. 4 No. 02 (2024): Volume 04 Issue 02 February 2024
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Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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