Prevalence and Risk Factors for Recurrence of Basal Cell Carcinoma Following Surgical Excision in a 5-Year Follow-Up Period
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Abstract
Material And Methods: Observational, descriptive, retrospective study in patients with clinical and histopathological diagnosis of basal cell carcinoma, attended at CMN La Raza in a period of 5 years, to determine the postoperative recurrence of CBC. Clinical and histological variables were included, which were analyzed with descriptive statistics and for the comparison of variables was used chi-square or exact test of Fisher and U of Mann Whitney, subsequently, multiple logistic regression was performed to determine the independent risk factors, with the use of the statistical package SPSS v25. The study was approved by the ethics and research committee of CMN La Raza.
Results: We included 280 patients with CBC, with a median age of 72 years. The majority were 211 women (75.4%). CBC recurrence was observed in 115 (41.1%) patients. In the univariate analysis, age, sex, smoking, history of sunburn, facial area, CBC subtype, perineural and vascular involvement were found to be statistically significant (p<0.05). In the regression model, the independent risk factors associated with postoperative recurrence of CBC were age, male sex, and smoking.
Conclusions: The clinical-pathological characteristics were similar to those reported in the literature. In our population, it was observed as independent risk factors for recurrence, adjusted to those already mentioned in the literature, were male sex, age and smoking, so it is important to closely monitor these patients to take measures regarding surgical treatment.
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