Rationality of the Antibiotics Use in Pediatric Acute Respiratory Infection Patients at Ssma Hospital in Pontianak, Indonesia
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Abstract
Acute respiratory tract infections (ARI) in children have a high prevalence that can be caused by bacteria or viruses. Antibiotics are prescribed more often than recommendations in the guidelines. This study aims to evaluate the rationality of antibiotic use and the occurrence of drug interactions in pediatric patients diagnosed with ARI at one of the hospitals in Pontianak based on some parameters such as right drug, right dose, and right duration as well as the incidence of drug interactions. Data collection was carried out based on medical record data which was carried out with a total sampling technique, namely taking all data that met the inclusion criteria.This research is a descriptive cross sectional design and retrospective data collection using patient medical records. Samples were taken by total sampling method. The results obtained from 131 patients consisting of 172 visits, right drug (131), right dose (93), and right duration (77).
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References
I. Canet JJ, Garau J. Importance of Dose and Duration of Beta-lactam Therapy in Nasopharyngeal Colonization with Resistant Pneumococci. J Antimicrobial Chemotheraphy. 2002: 49-53.
II. Dyah NW, Sondakh R. The Relationship between Structure and Process of Drug Metabolism. In Medicinal Chemistry. Edition II. Editors: Siswondono and B. Soekardjo. Surabaya: Airlangga University Press. 2008: p. 63.
III. Harvey TC, Fowler RA, Daneman N. Duration of Antibiotic Therapy for Bacteremia: A Systematic Review and Meta-analysis. Crit Care. 2011; 15 (6): 267.
IV. Fibrila F. Relationship between Child's Age, Gender, and Child Birth Weight with the incidence of ARI. Metro Health Journal. 2015; 8 (2): 8-13.
V. Leclercg S, Mian FM, Stanisz AM, Bindels LB, Cambier E, Ben-Amram H, et al. Low-dose Penicillin in Early Life Induces Long-term Changes in Murine Gut Microbiota, Brain Cytokines and Behavior. Nat Commun. 2017; 4 (8).
VI. Ministry of Health of the Republic of Indonesia. General Guidelines for Use of Antibiotics. Jakarta: Ministry of Health of the Republic of Indonesia; 2011.
VII. Ranny, Liviandari Ranantha. The Relationship between Toddler Characteristics and the Incidence of ARI in Toddlers in Gandon Village, Kaloran District, Temanggung Regency.
[http://eprints.dinus.ac.id]. Retrieved 15 May 2019.
VIII. Said M. Textbook of Child Respirology. Edition I. Jakarta: IDAI Publishing Agency (Indonesian Pediatrician Association); 2008.
IX. Susanti M. Factors Affecting the Incidence of Recurrent ISPA in Toddlers at the Children's Clinic at the Islamic Hospital, Jakarta Cempaka Putih. Faculty of Nursing UMJ; 2015
X. Wang YC, Lipsitch M. Upgrading Antibiotic Use Within A Class: Tradeoff Between Resistance and Treatment Succes. PNAS. 2006; 103(25): 9655-9660.