Delirium Management in the Critic Geriatric Patient: An Updated Approach

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Marisol Hernández Ortiz
Mayra Cristina Rodríguez García
Rebeca Espinoza Fuerte
Samanta Ruiz
Elizama Saraí Gómez Arpaiz

Abstract

Delirium or acute confusional syndrome is a common problem in geriatric patients, although its diagnosis is often overlooked, especially in its hypoactive form. Risk factors for delirium are previous cognitive alterations and certain comorbidities, different environmental factors and acute organic alterations typical of critically ill patients. Delirium is associated with increased short- and long-term mortality, to the prolongation of mechanical ventilation, to prolonged stays in the Intensive Care Unit (ICU) and in the hospital and to cognitive deterioration after hospital discharge. In recent years, specific tools have been developed for the detection of delirium in ICU.


The implementation of specific interventions on certain risk factors can reduce the incidence of delirium in hospitalized patients. The treatment of delirium it is based on identifying and correcting the underlying causes, establishing support measures and, sometimes, pharmacological treatment to control symptoms. Haloperidol is the first-line drug for the control of delirium, since experience with atypical neuroleptics, such as olanzapine and risperidone, as well as with other drugs, it is insufficient to be able to make recommendations on their use. Neuroleptics can have serious side effects that must be taken into account. In cases with agitation, the simultaneous use of benzodiazepines or propofol may be necessary and, sometimes, in a temporary and protocolized manner, the use of physical restraints.

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How to Cite
Hernández Ortiz, M. ., Rodríguez García, M. C. ., Fuerte, R. E., Ruiz, S. ., & Gómez Arpaiz, E. S. . (2022). Delirium Management in the Critic Geriatric Patient: An Updated Approach. International Journal of Medical Science and Clinical Research Studies, 2(11), 1325–1328. https://doi.org/10.47191/ijmscrs/v2-i11-35
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Articles

References

I. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text revision. Washington DC, American Psychiatric Association 2000.

II. Ely EW, Siegel MD, Inouye SK. Delirium in the Intensive Care Unit: an under-recognized syndrome of organ dysfunction. Seminars Respir Crit Care Med. 2001; 22:115-6.

III. Ely EW, Stephens RK, Jackson JC, Thomason JW, Truman B, Gordon S, et al. Current opinions regarding the importance, diagnosis, and management of delirium in the intensive care unit: a survey of 912 healthcare professionals. Crit Care Med. 2004; 32:106-12.

IV. Ely EW, Gautam S, Margolin R, Francis J, May L, Speroff T, et al. The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med. 2001; 27:1892-1900.

V. Ely EW, Shintani A, Truman B, Speroff T, Gordon SM, Harrell FE, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the Intensive Care Unit. JAMA. 2004; 291:1753-62.

VI. Laurila JV, Pitkala KH, Strandberg TE, Tilvis RS. The impact of different diagnostic criteria on prevalence rates for delirium. Dementia Geriatr Cognit Dis. 2003; 16:156-61.

VII. González M, De Pablo J, Fuente E, Valdés M, Peri JM, Nomdedeu M, et al. Instrument for detection of delirium in general hospitals: adaptation of confusion assessment method. Psychosomatics. 2004; 45:426-31.

VIII. Guillén Lera F. Delirium en pacientes ancianos hospitalizados. Med Clin (Barc.). 2005; 124:538-40.

IX. Ely EW, Inouye SK, Bernard GR, Gordon S, Francis J, May L, et al. Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA. 2001; 286:2703-10

X. Ely EW, Margolin R, Francis J, May L, Truman B, Dittus R, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med. 2001; 29:1370-9.

XI. Bergeron N, Dubois MJ, Dumont M, Dial S, Skrobik Y. Intensive Care Delirium Scrrening Checklist: evaluation of a new screening tool. Intensive Care Med. 2001; 27:859-64.

XII. Ely EW, Truman B, Shintani A, Thomason JW, Wheeler AP, Gordon S, et al. Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond AgitationSedation Scale (RASS). JAMA. 2003; 289:2983-91.

XIII. Laurila JV, Pitkala KH, Strandberg TE, Tilvis RS. Confusion assessment method in the diagnostics of delirium among aged hospital patients: would it serve better in screening than as a diagnostic instrument? Int J Geriatr Psychiatry. 2002; 17:1112-9.

XIV. Bergeron N, Skrobik Y, Dubois MJ. Is disturbance of consciousness an important feature of ICU delirium? Intensive Care Med. 2005; 31:887.

XV. Lin SM, Liu CY, Wang CH, Lin HC, Huang CD, Huang PY, et al. The impact of delirium on the survival of mechanically ventilated patients. Crit Care Med. 2004; 32:2254-9.

XVI. Inouye SK, Bogardus ST Jr, Charpentier PA, Leo-Summers L, Acampora D, Holford TR, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. N Engl J Med. 1999; 340:669-76.

XVII. Meagher DJ, O’Hanlon D, O’Mahony E, Casey PR, Trzepacz PT. Relationship between symptoms and motoric subtype of delirium. J Neuropsychiatry Clin Neurosci. 2000; 12:51-6.

XVIII. O’Keefe ST, Lavan JN. Clinical significance of delirium subtypes in older people. Age Ageing. 1999; 28:115-9.

XIX. Levkoff SE, Evans DA, Liptzin B, Cleary PD, Lipsitz LA, Wetle TT, et al. Delirium. The occurrence and persistence of symptoms among elderly hospitalized patients. Arch Intern Med. 1992; 152:334-40.

XX. McNicoll L, Pisani MA, Zhang Y, Ely EW, Siegel MD, Inouye SK. Delirium in the intensive care unit: occurrence and clinical course in older patients. J Am Geriatr Soc. 2003; 51:591-8.

XXI. Kiely DK, Bergmann MA, Murphy KM, Jones RN, Orav EJ, Marcantonio ER. Delirium among newly admitted postacute facility patients: prevalence, symptoms, and severity. J Gerontol A Biol Sci Med Sci. 2003;58:M441-5.

XXII. Breitbart W, Rosenfeld B, Roth A, Smith MJ, Cohen K, Passik S. The Memorial Delirium Assessment Scale . J Pain Symptom Manage. 1997; 13:128-37.

XXIII. McCusker J, Cole M, Bellavance F, Primeau F. Reliability and validity of a new measure of severity of delirium. Int Psychogeriatr. 1998; 10:421-33.

XXIV. Skrobik YK, Bergeron N, Dumont M, Gottfried SB. Olanzapine vs haloperidol: treating delirium in a critical care setting. Intensive Care Med. 2004; 30:444-9.