Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) Related to Breast Implants: A Comprehensive Review

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Published: Oct 23, 2024
DOI: https://doi.org/10.47191/ijmscrs/v4-i10-32
Keywords:
ASIA syndrome, Breast implant illness, Autoimmune diseases, Silicone adjuvants, Inflammatory response, Explantation, Autoimmunity, Breast implants, Adjuvant-induced disease, Silicone-induced autoimmunity.

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Héctor Cisneros Pérez
Hospital del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Zacatecas. Zacatecas, Zacatecas, Mexico.
Mario Hernandez Mancillas
Hospital del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Zacatecas. Zacatecas, Zacatecas, Mexico.
Marina Gallegos Colón
Hospital del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Zacatecas. Zacatecas, Zacatecas, Mexico.
Luis Jorge Caldera Sanchez
Hospital del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado Za
Omar Guadalupe Dorado Hernandez
Hospital General de Zacatecas "Luz González Cosio". Secretaria de salud. Zacatecas, Zacatecas, México.

Abstract

Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) is a complex clinical entity characterized by the onset of autoimmune or inflammatory responses following exposure to adjuvants, substances that enhance immune responses. One of the most studied triggers of ASIA is breast implants, which are commonly composed of silicone. While breast implants are generally considered safe, a subset of patients may develop systemic symptoms collectively termed as "Breast Implant Illness" (BII), now recognized within the broader spectrum of ASIA. This review provides a thorough analysis of the pathophysiology, clinical presentation, diagnostic challenges, and management options for ASIA associated with breast implants. We aim to elucidate the underlying mechanisms of immune dysregulation and inflammatory responses induced by silicone and explore the latest evidence-based therapeutic approaches, including explantation surgery and immunosuppressive therapies. Our review underscores the need for heightened clinical awareness and further research into ASIA, as early recognition and intervention can significantly improve patient outcomes.

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How to Cite
Héctor Cisneros Pérez, Mario Hernandez Mancillas, Marina Gallegos Colón, Luis Jorge Caldera Sanchez, & Omar Guadalupe Dorado Hernandez. (2024). Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA) Related to Breast Implants: A Comprehensive Review. International Journal of Medical Science and Clinical Research Studies, 4(10), 1900–1908. https://doi.org/10.47191/ijmscrs/v4-i10-32
Issue
Vol. 4 No. 10 (2024): Volume 04 Issue 10 October 2024
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Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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