Pathomechanisms, Pathophysiology and Biomechanics of Degenerative Spine Disease: A Review of Literature

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Published: Mar 13, 2024
DOI: https://doi.org/10.47191/ijmscrs/v4-i03-21
Keywords:
intervertebral disc, disc degeneration, biomechanisms, spine, low back pain

Main Article Content

Ogunleye OO
Department of Surgery, Abubakar Tafawa Balewa University Bauchi, Nigeria
Adamu A
Department of Otorhinolaryngology, Abubakar Tafawa Balewa University Bauchi, Nigeria
Baffah AM
Department of Obstetrics and Gynaecology, Abubakar Tafawa Balewa University Bauchi, Nigeria
Essien OB
Department of Chemical Pathology, University of Calabar, Calabar, Nigeria
Bwala KJ
Department of Surgery, Abubakar Tafawa Balewa University Bauchi, Nigeria
Ballah AM
Department of Anaesthesiology, Abubakar Tafawa Balewa University Bauchi, Nigeria
Kirfi AM
Department of Otorhinolaryngology, Abubakar Tafawa Balewa University Bauchi, Nigeria
Abdul MM
Department of Ophthalmology, Abubakar Tafawa Balewa University Bauchi, Nigeria
Duke R
Department of Ophthalmology, University of Calabar, Calabar, Nigeria

Abstract

The intervertebral disc in human being is a complex structure and is made up of fibrous and cartilaginous tissues. It is characterized as tension-resisting structure while it allows limited range of motion in axial, bending or rotational posture. Degenerative process of this structure present with clinical morbidity to the patients and possess great challenges to the clinicians while offering care for disc’s pathology. Degeneration begins with imbalance of homeostasis maintained by content of nucleus pulposus and annulus fibrosus. Numerous factors; genetic, mechanical and nutritional, can initiate and or accelerate this degeneration process which ultimately alter the biomechanics of the spine. The aim of this review is to give an overview on the degeneration process, causes and factors influencing disc degeneration, the mechanisms of degeneration and the changes resulted from intervertebral disc degeneration.

Article Details

How to Cite
Ogunleye OO, Adamu A, Baffah AM, Essien OB, Bwala KJ, Ballah AM, Kirfi AM, Abdul MM, & Duke R. (2024). Pathomechanisms, Pathophysiology and Biomechanics of Degenerative Spine Disease: A Review of Literature. International Journal of Medical Science and Clinical Research Studies, 4(03), 484–489. https://doi.org/10.47191/ijmscrs/v4-i03-21
Issue
Vol. 4 No. 03 (2024): Volume 04 Issue 03 March 2024
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

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