Schamberg's Purpura: A Comprehensive Review of Clinical Manifestations, Pathophysiology, and Management Strategies
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Abstract
Schamberg's Purpura, also known as progressive pigmented purpura or Schamberg disease, is a dermatological condition characterized by a distinctive purpuric rash. This article provides a thorough examination of the clinical manifestations, pathophysiological mechanisms, and current management approaches associated with this intriguing disorder. The review aims to consolidate existing knowledge, highlight diagnostic challenges, and explore emerging therapeutic interventions. Through an in-depth analysis of the latest research findings, this comprehensive overview aims to enhance the understanding of Schamberg's Purpura among healthcare professionals, facilitating more accurate diagnosis and improved patient outcomes.
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References
I. Zvulunov A, Avinoach I, Hatskelzon L, Halevy S. Pigmented purpuric dermatosis (Schamberg's purpura) in an infant. Dermatol Online J. 1999 May;5(1):2.
II. RANDALL SJ, KIERLAND RR, MONTGOMERY H. Pigmented purpuric eruptions. AMA Arch Derm Syphilol. 1951 Aug;64(2):177-91.
III. Tristani-Firouzi P, Meadows KP, Vanderhooft S. Pigmented purpuric eruptions of childhood: a series of cases and review of literature. Pediatr Dermatol. 2001 Jul-Aug;18(4):299-304.
IV. Sardana K, Sarkar R, Sehgal VN. Pigmented purpuric dermatoses: an overview. Int J Dermatol. 2004 Jul;43(7):482-8.
V. Ratnam KV, Su WP, Peters MS. Purpura simplex (inflammatory purpura without vasculitis): a clinicopathologic study of 174 cases. J Am Acad Dermatol. 1991 Oct;25(4):642-7.
VI. Bonnet U, Selle C, Isbruch K, Isbruch K. Recurrent purpura due to alcohol-related Schamberg's disease and its association with serum immunoglobulins: a longitudinal observation of a heavy drinker. J Med Case Rep. 2016 Oct 31;10(1):301.
VII. Koçak AY, Akay BN, Heper AO. Sildenafil-induced pigmented purpuric dermatosis. Cutan Ocul Toxicol. 2013 Mar;32(1):91-2.
VIII. Voelter WW. Pigmented purpuric dermatosis-like reaction to topical fluorouracil. Arch Dermatol. 1983 Nov;119(11):875-6.
IX. 9.Schetz D, Kocić I. A new adverse drug reaction--Schamberg's disease caused by amlodipine administration--a case report. Br J Clin Pharmacol. 2015 Dec;80(6):1477-8.
X. Nishioka K, Katayama I, Masuzawa M, Yokozeki H, Nishiyama S. Drug-induced chronic pigmented purpura. J Dermatol. 1989 Jun;16(3):220-2.
XI. Abeck D, Gross GE, Kuwert C, Steinkraus V, Mensing H, Ring J. Acetaminophen-induced progressive pigmentary purpura (Schamberg's disease). J Am Acad Dermatol. 1992 Jul;27(1):123-4.
XII. Kanwar AJ, Thami GP. Familial Schamberg's disease. Dermatology. 1999;198(2):175-6.
XIII. 13.Aiba S, Tagami H. Immunohistologic studies in Schamberg's disease. Evidence for cellular immune reaction in lesional skin. Arch Dermatol. 1988 Jul;124(7):1058-62.
XIV. 14.Sharma L, Gupta S. Clinicoepidemiological study of pigmented purpuric dermatoses. Indian Dermatol Online J. 2012 Jan;3(1):17-20.