From Pathophysiology of Rosacea to Clinical Care
Main Article Content
Abstract
Rosacea, a dermatologic disorder characterized by persistent facial erythema, papules, and pustules, often accompanied by ocular involvement, poses diagnostic and therapeutic challenges. This review comprehensively explores the clinical presentation, diagnostic criteria, differential diagnosis, and management strategies for rosacea. Emphasizing the multifactorial nature of its pathogenesis, including genetic and immune components, the review underscores the importance of individualized treatment approaches. Specialist referrals, especially for refractory cases, and a diverse range of treatment modalities, from topical medications to laser therapies, contribute to effective management. Regular monitoring and early intervention mitigate complications, ensuring a favorable prognosis. Ongoing research enhances our understanding of rosacea, guiding advancements in its diagnosis and management.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
I. Johnson, S. M., Berg, A., & Barr, C. (2020). Managing Rosacea in the clinic: from pathophysiology to treatment—a review of the literature. The Journal of Clinical and Aesthetic Dermatology, 13(4 Suppl 1), S17.
II. van Zuuren, E. J., Arents, B. W., van der Linden, M. M., Vermeulen, S., Fedorowicz, Z., & Tan, J. (2021). Rosacea: new concepts in classification and treatment. American journal of clinical dermatology, 22(4), 457-465.
III. Zhang, H., Tang, K., Wang, Y., Fang, R., & Sun, Q. (2021). Rosacea treatment: review and update. Dermatology and therapy, 11, 13-24.
IV. Lerner, E. A., & Cevikbas, F. (2020). Pathophysiology of Rosacea. Rosacea, 15-21.
V. Wilkin, J. K., & McGee, J. S. (2020). Introduction to Clinical Rosacea. Rosacea, 1-13.
VI. Cribier, B. (2022, June). Rosacea: Treatment targets based on new physiopathology data. In Annales de Dermatologie et de Vénéréologie (Vol. 149, No. 2, pp. 99-107). Elsevier Masson.
VII. Tavassoli, S., Wong, N., & Chan, E. (2021). Ocular manifestations of rosacea: a clinical review. Clinical & Experimental Ophthalmology, 49(2), 104-117.
VIII. Tan, J., Singh, B., Song, Y., Zaher, O., Arents, B. W., Schaller, M., & van Zuuren, E. J. (2021). Rosacea treatments: current standards and additional options. Dermatological Reviews, 2(6), 357-378.
IX. Elwan, N. M., Salah, S. M., Abdelsalam, S. F., & Elfar, N. N. (2020). Role of ferritin in pathogenesis of rosacea and its value in efficacy of 595 nm pulsed dye laser in treatment of different variants of rosacea: a clinical and immunohistochemical study. Journal of Cosmetic and Laser Therapy, 22(3), 130-136.
X. Vassileva, S., Tanev, I., & Drenovska, K. (2023). Rosacea: The eyes have it. Clinics in Dermatology.