A Randomized, Open Labeled Clinical Survey To Evaluate The Anti-Viral, Anti-Inflammatory and Immune Modulator Role of Polyherbal Combinations in Viral Infections of Respiratory Tract

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Dr.Smita Naram
Dr. Deepak Mahajan
Dr. Hemang Parekh

Abstract

Cough is the common reflex produced for upper respiratory tract infections (URTI), however, a cough can also be a symptom of other hidden conditions like asthma or other lung diseases. The immune modulation with Ayurvedic formulations as possible therapeutic measures is the need of time. Ancient Indian medicinal system of Ayurveda has a wide scope for treating many diseases by the theory of Rasayana. Rasayana in other terms are called as preparations from plant or herbal sources which have immunomodulatory properties. As this is a Pilot study each participant is supplied with the Swaswin D Vyro (Virofight) 625 mg two tablets twice a day, Swaswin Asthaloc 600 mg two tablets twice a day, Syrup Swaswin Kaphano 5 ml twice a day after food with lukewarm water at each visit.The results were assessed with a scale developed by Ayushakti Ayurveda Pvt Ltd. The scale is general, and self-administered. It consists of seven symptoms in the respiratory tract. Individual scale symptom responses are assigned a score between 0 (none) to 10 (Extreme). Total assessment of the result was done on the basis of relief from symptoms of the disease.This combination is helpful for viral infection of healthy individuals as well as in asthma-like chronic conditions of the respiratory tract, including patients with comorbid conditions. This combination acts as an antiviral, anti-inflammatory, antispasmodic, immune modulatory and antitussive.

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How to Cite
Naram , D., Mahajan, D. D. ., & Parekh , D. H. (2022). A Randomized, Open Labeled Clinical Survey To Evaluate The Anti-Viral, Anti-Inflammatory and Immune Modulator Role of Polyherbal Combinations in Viral Infections of Respiratory Tract. International Journal of Medical Science and Clinical Research Studies, 2(2), 147–153. https://doi.org/10.47191/ijmscrs/v2-i2-12
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References

I. Veronica L, Toxicity of Over-the-Counter Cough and Cold Medications, Journal of the American Academy of Pediatrics, Pediatrics September 2001, 108 (3) e52;

DOI: https://doi.org/10.1542/peds.108.3.e52

II. Infectious-diseases respiratory-viruses/overview-of viral-respiratory-infections https://www.msdmanuals. Com/professional

III. Dasaraju PV, Liu C. Infections of the Respiratory System. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 93.

IV. Rege NN, Thatte UM, Dahanukar SA. Adaptogenic properties of six rasayana herbs used in Ayurvedic medicine. Phytother Res. 1999; 13(4):275–291. doi: 10.1002/(SICI)1099-1573(199906)13:43.0. CO;2-S 5. Atal CK, Sharma M

V. Melvin R.Pratter, Cough and the Common Cold: ACCP Evidence-Based Clinical Practice Guidelines, CHEST, Volume 129, Issue 1, Supplement, January 2006,

VI. Song WJ, Chang YS. Cough hypersensitivity as a neuro-immune interaction. Clin Transl Allergy. 2015;5:24. Published 2015 Jul 15.

doi:10.1186/s13601-015-0069-4

VII. Panda A, Doddanagali SR. Clinical efficacy of herbal Padmapatradi yoga in bronchial asthma (Tamakashwasa) J Ayurveda Integr Med. 2011;2:85-90.

VIII. Suekawa M, Ishige A, Yuasa K, Sudo K, Aburada M, Hosoya E, Pharmacological studies on ginger. I. Pharmacological actions of pungent constitutents, (6)-gingerol and (6)-shogaol. J Pharmacobiodyn. 1984;7(11):836-48

IX. Asami A, Shimada T, Mizuhara Y, Asano T, Takeda S, Aburada T, et al. Pharmacokinetics of [6]-shogaol, a pungent ingredient of Zingiber officinale Roscoe (Part I). J Natural Medic. 2010;64(3):281-7.

X. Amit A, Saxena VS, Pratibha N, D'Souza P, Bagchi M, Bagchi D, et al. Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis., Drugs Exp Clin Res. 2003;29(3):107-15.

XI. Choudhary GP. Mass cell stabilizing activity of Piper longum Linn. Indian J Allerg Asthma Immunol. 2006; 20:112-6.

XII. Chauhan K, Phytochemical and therapetics Potential of Piper Longum Linn-A Review, IJRAP. 2011;2(1) 157-61

XIII. Pathak AK, Nainwal N, Goyal BM, Singh R, Mishra V, Nayak S, et al. Pharmacological activity of Trachyspermumammi: A Review; J

XIV. Karande SP et al. A double blind, randomized, placebo controlled, phase IV, proof-of-concept, comparative study to evaluate the efficacy and safety of Swasawin asthaloc tablets when given as add-on therapy in patients suffering from mild to moderate persistent bronchial asthma Int J Res Med Sci. 2017 Nov;5(11):4929-4936

www.msjonline.org

XV. Megha Murali, Ragini Kumari, Kirti Soni, Sujeet Kumar. Therapeutic Action of Hingu In Respiratory System: A Literary Review International Journal of Ayurveda and Pharma Research. 2020;8(12):37-42

XVI. Naram, Tablet Swasvin D Vyro (Virofight) - A Proven Solution for any Viral Infection, Immunity and Inflammation. Global Journal of Medical Research. 7-12. 10.34257/GJMRBVOL20IS5PG7.

XVII. Cristina Fiore Michael Eisenhut, Antiviral effects of Glycyrrhiza species, PHYTOTHERAPY RESEARCH Phytother. Res. 22, 141–148 (2008) Published online20 September 2007 in Wiley Inter Science (www.interscience.wiley.com) DOI: 10.1002/ptr.2295 https://doi.org/10.1002/ptr.2295.

XVIII. K. P. Sampath Kumar et al ,Indian traditional herbs Adhatoda vasica and its Medicinal application, J. Chem. Pharm. Res., 2010, 2(1): 240-245

XIX. M.S. Harsoliya et al. Anti tussive effect of multi uses medicinal plants on sulfur dioxide gas induced cough reflex in mice Journal of Pharmacy Research 2011,4(11),4123-4125.