Lupus nephritis: A Comprehensive Review

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Published: Aug 31, 2023
DOI: https://doi.org/10.47191/ijmscrs/v3-i8-62
Keywords:
Lupus nephritis, SLE, diagnosis, treatment, complications.

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Jacob Bueno Cante
Hospital General Zona Norte de Puebla
Sergio Sandoval Velázquez
Hospital General Zona Norte de Puebla
Sofia Cayetana Aguilar Mendez
Hospital General Zona Norte de Puebla

Abstract

Definition: Lupus nephritis involves chronic inflammation of kidney tissue in patients with SLE, which can lead to structural and functional damage.


Clinical Manifestations: Its symptoms range from mild, such as proteinuria and hematuria, to severe, including kidney failure. Patients may experience fatigue, swelling, and changes in urination.


Diagnosis: Based on clinical findings, urinalysis, serological tests, and renal biopsies to assess severity and guide treatment.


Treatment: Includes corticosteroids and other immunosuppressants. The therapy is personalized and closely supervised by a multidisciplinary team.


Complications: Chronic kidney failure, cardiovascular disease, and infections are major concerns. Patient education and comprehensive care are crucial.

Article Details

How to Cite
Cante, J. B. ., Velázquez, S. S., & Cayetana Aguilar Mendez, S. . (2023). Lupus nephritis: A Comprehensive Review. International Journal of Medical Science and Clinical Research Studies, 3(8), 1767–1769. https://doi.org/10.47191/ijmscrs/v3-i8-62
Issue
Vol. 3 No. 8 (2023): Volume 03 Issue 08 August 2023
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

References

I. Berden, H. J. (1997). Lupus nephritis. Kidney international, 52(2), 538-558.

II. Almaani, S., Meara, A., & Rovin, B. H. (2017). Update on lupus nephritis. Clinical journal of the American Society of Nephrology: CJASN, 12(5), 825.

III. Borchers, A. T., Leibushor, N., Naguwa, S. M., Cheema, G. S., Shoenfeld, Y., & Gershwin, M. E. (2012). Lupus nephritis: a critical review. Autoimmunity reviews, 12(2), 174-194.

IV. Balow, J. E., AUSTIN III, H. A., TSOKOS, G. C., ANTONOVYCH, T. T., STEINBERG, A. D., & KLIPPEL, J. H. (1987). Lupus nephritis. Annals of Internal Medicine, 106(1), 79-94.

V. Imran, T. F., Yick, F., Verma, S., Estiverne, C., Ogbonnaya-Odor, C., Thiruvarudsothy, S., ... & Kothari, N. (2016). Lupus nephritis: an update. Clinical and experimental nephrology, 20, 1-13.

VI. Henderson, L., Masson, P., Craig, J. C., Flanc, R. S., Roberts, M. A., Strippoli, G. F., & Webster, A. C. (2012). Treatment for lupus nephritis. Cochrane Database of Systematic Reviews, (12).